北海道大学電子科学研究所 生体分子デバイス研究分野

2008年

Stabilization of DNA Multiassembly by Addition of a Phosphate Group at the 5′-Sticky End
A. Tanaka, Y. Matsuo, K. Niikura, *K. Ijiro
Chem. Lett., 37, 758-759 (2008)

Sequence-specifically platinum metal deposition on enzymatically synthesized DNA block copolymer
A. Tanaka, Y. Matsuo, K. Niikura, *K. Ijiro
Chem. Commun., 36, 4270-4272 (2008)

Oligosaccharide-mediated Nuclear Transport of Nanoparticles
K. Niikura, S. Sekiguchi, T. Nishio, T. Masuda, H. Akita, Y. Matsuo, K. Kogure, H. Harashima, K. Ijiro
ChemBioChem?, 9, 2623-2627 (2008)

Sequence-Spesific Control of Azobenzene Assemblies by Molecular Recognition of DNA
O. Haruta, Y. Matsuo, Y. Hashimoto, K. Niikura, K. Ijiro
Langmuir, 24, 2618-2624 (2008)

Photo-induced fluorescence emission of azobenzene thin films
O. Haruta, Y. Matsuo,K. Ijiro
Colloid and Surfaces A, 1, 313-314 (2008)

Enhanced cellular uptake of virus-like particles through immobilization on sialic acid-displaying solid surface
N. Ohtake, K. Niikura, T. suzuki, K. Nagakawa, H. sawa, K. Ijiro
Bioconjugate Chemistry, 19(2), 507-515 (2008)

Development of lipid particles targeted via sugar-lipid conjugates as novel nuclear gene deliverly system
T. Masuda, H. Akita, T. Nishio, K. Nikura, A. Kudo, K. Kogure, K. Ijiro, H. Hakashima
Biomaterials, 29, 209-723 (2008)

2007年

“Patterned Immobilization of Unprotected Carbohydrates on an Aminooxy Polymer-Grafted Solid Surface”
R. Kamitani, K. Niikura, T. Onodera, N. Iwasaki, H. Shimaoka, and K. Ijiro
Bulletin of the Chemical Society of Japan, in press (2007)

“Application of Oligonucleotide as a Template for the Assembly of Nucleoamphiphile Bearing Azobenzene at the Air-Water Interface”
O. Haruta and K. Ijiro ,
Journal of Nanoscience and Nanotechnology, 7, 734-737 (2007)

“Accumulation of O-GlcNAc-displaying CdTe? Quantum Dots in Cells in the presence of ATP”,
K. Niikura, T. Nishio, H. Akita, Y. Matsuo, R. Kamitani, K. Kogure, H. Harashima, and K. Ijiro ChemBioChem?, 8(4), 379-384 (2007)

「血管内皮細胞の初期伸展に及ぼすハニカムフィルム細孔径の影響」
山本貞明、田中賢、伊藤絵美子、森田有香、角南寛、居城邦治、下村政嗣表面科学、8(8)、433-439 (2007)

2006年

“Immobilizing and stretching of poly(dG)–poly(dC) synthesized by Klenow fragment exo− on substrates by LB method”
A. Tanaka, Y. Matsuo and K. Ijiro
Colloids and Surfaces A, 284-285, 246-249 (2006)

Circular arrangement of nucleoamphiphile containing azobenzene by using base pairing with cyclic oligonucleotide template at the air–water interface”
O. Haruta, J. Nishida and K. Ijiro , Colloids and Surfaces A, 284-285, 326-330 (2006)

“Highly expansive DNA hydrogel films prepared with photocrosslinkable poly(vinyl alcohol)”
N. Ishizuka, Y. Hashimoto, Y. Matsuo and K. Ijiro
Colloids and Surfaces A, 284-285, 440-443 (2006)

“DNA-Based Silver Nanowires Fabricated By Electroless Plating”
K. Ijiro, Y. Matsuo, and Y. Hashimoto
Mol. Cryst. Liq. Cryst., 445, 207(497)-211(501) (2006)

“Stripe Pattern Formation of Oligonucleotides by Langmuir-Blodgett Method”
Y. Matsuo, and K. Ijiro
International Journal of Nanoscience, 5(6), 697-701 (2006)

2005年

“Fabrication of Silver Nanowires by Selective Electroless Plating of DNA Stretched Using the LB Method”
Y. Hashimoto, Y. Matsuo, and K. Ijiro
Chem. Lett., 34, 112-113(2005)

Y“Stretching of Single DNA Molecules Complexed with Restriction Endonuclease by Langmuir-Blodgett Method”
.Matsuo, K. Ijiro, and M. Shimomura
Colloids and Surfaces B: Biointerfaces, 40(4), 123-126 (2005)

“Fabrication of Metal Nanowires by Electroless Plating of DNA”
K. Ijiro, Y. Matsuo, and Y. Hashimoto
e-J. Surf. Sci. Nanotech., 3, 82-85(2005)

“Fabrication of Silver Nanowires based on DNA stretched by the LB Method”
Y. Hashimoto, Y. Matsuo, and K. Ijiro
Transactions of the Materials Research Society of Japan, 30(3), 671-674 (2005)

“Spontaneous Formation of Polymer Nanoparticles by Good-solvent Evaporation as Non-equilibrium Process”
H. Yabu, T. Higuchi, K. Ijiro, and M. Shimomura
Chaos, 15, 4, 047505 (2005)

Chemical and Enzymatic Synthesis of Glycocluster Having Seven Sialyl Lewis X Arrays Using b-Cyclodextrin as a Key Scaffold Material
“Tetsuya Furuike, Reiko Sadamoto, Kenichi Niikura, Kenji Monde, Nobuo Sakairi and Shin-Ichiro Nishimura”
“Tetrahedron,61(7),1737-1742,2005”

Versatile Glycoblotting Nanoparticles for High Throughput Protein Glycomics
“Kenichi Niikura, Ryousuke Kamitani, Masaki Kurogochi, Rie Uematsu, Yasuro Shinohara, Hiroaki Nakagawa, Kisaburo Deguchi Kenji Monde, Hiroshi Kondo, Shin-Ichiro Nishimura,”
“Chemistry – A European Journal,11(13),3825-3835,2005”

An engineered hyaluronan synthase: Characterization of recombinant human hyaluron synthetase 2 expressed in Escherichia coli.
“Hiroko Hoshi, Hiroaki Nakagawa, Susumu Nishiguchi, Kazumichi Iwata, Kenichi Niikura, Kenji Monde, and Shin-Ichiro Nishimura”
“The Journal of Biological Chemistry,279,2341-2349,2004”

2004年

Site specific introduction of sialic acid into insulin
“Masaaki Sato, Reiko Sadamoto, Kenichi Niikura, Kenji Monde, Hirosato Kondo, Shin-Ichiro Nishimura ”
“Angewandte Chemie International Edition,43,1516-1520,2004”

Flurescent glyconanoparticles as a sensitive device to monitor sugar-involving molecular events
“Kenichi Niikura, Noriko Osuga, Noriko Nagahori, Reiko Sadamoto, Masamichi Shiono, Norimasa Iwasaki, Kenji Monde, Akio Minami and Shin-Ichiro Nishimura”
“Polymer Journal,36,209-218,2004”

A practical synthesis of amphiphilic cyclodextrins fully substituted with sugar on the primary face
“Florence Sallas, Kenichi Niikura, Shin-Ichiro Nishimura”
“Chemical Communications ,5,596-597,2004”

Control of bacterial adhesion by cell-wall engineering
“Reiko Sadamoto, Kenichi Niikura, Taichi Ueda, Kenji Monde, Norio Fukuhara, and Shin-Ichiro Nishimura”
“Journal of the American Chemical Society,126,3755-3761,2004”

Chemo-enzymatic synthesis of fluorinated 2-N-acetamidosugar nucleotides using UDP-GlcNAc pyrophosphorylase
“Fei Feng, Kiyoshi Okuyama, Kenichi Niikura, Takashi Ohta, Reiko Sadamoto, Kenji Monde, Toshitada Noguchi, Shin-Ichiro Nishimura”
“Organic & Biomolecular Chemistry,2,1617-16213,2004”

Synthesis of 4-fluorinated UDP-MurNAc pentapeptide as an inhibitor of bacterial growth
“Taichi Ueda, Fei Feng, Reiko Sadamoto, Kenichi Niikura, Kenji Monde, and Shin-Ichiro Nishimura”
“Organic Letters,6,1753-1756,2004”

Glyco-insulins: Dendritic sialyloligosaccharide-displaying insulins showing a prolonged blood-sugar lowering activity
“Masaaki Sato, Tetsuya Furuike, Reiko Sadamoto, Naoki Fujitani, Taku Nakahara, Kenichi Niikura, Kenji Monde, Hirosato Kondo, and Shin-Ichiro Nishimura”
“Journal of the American Chemical Society,126,14013-14022,2004”

Direct N-glycan profiling in the presence of tryptic peptides on MALDI-TOF by controlled ion enhancement and suppression upon glycan-selective derivatization
“Yasuro Shinohara, Jun-ichi Furukawa, Kenichi Niikura, Nobuaki Miura, and Shin-Ichiro Nishimura”
“Analytical Chemistry,76,6989-6997,2004”

High throughput protein glycomics: Combined use of chemoselective glycoblotting and MALDI-TOF/TOF mass spectrometry
“Shin-Ichiro Nishimura, Kenichi Niikura, Masaki Kurogochi, Takahiko Matsushita, Masataka Fumoto, Hiroshi Hinou, Ryousuke Kamitani, Hiroaki Nakagawa, Kisaburo Deguchi, Nobuaki Miura, Kenji Monde, Hirosato Kondo”
“Angewandte Chemie International Edition,44,91-96,2004”

2003年

DNA-Based Molecular Handling in Self-Organized Monolayers
“K. Ijiro, Y. Matsuo, M. Shimomura”
“Interface2003,,79-82,2003”

Stretching of single DNA molecules by LB technique for restriction site mapping
“Kuniharu Ijiro, Yasutaka Matsuo, Masatsugu Shimomura”
“Nucleic Acids Research Supplement,3,47-48,2003”

Preparation of Honeycomb-Patterned Polyimide Films by Self-Organization
“H. Yabu, M. Tanaka, K. Ijiro, M. Shimomura”
“Langmuir,19,6297-6300,2003”

DNA-mimetics: toward novel molecular devices habing molecular information
“M. Shimomura, R. Mitamura, J. Matsumoto, K. Ijiro”
“Synthetic Metals,133-134,473-475,2003”

2002年

Base pair mapping by chemical force microscopy on nucleobase self-assembled monolayers
“K. Ijiro, H. Sunami, K. Arai, J. Matsumoto, O. Karthaus, S. Kraemer, S. Mittler, N. Nishi, B. Juskowiak, S. Takenaka, W. Knoll, M. Shimomura”
“Colloids and Surfaces,A:198-200,677-682,2002”

Preparation of Self-Organized Micro-Patterned Polymer Films Having Cell Adhesive Ligands
“J. Nishida, K. Nishikawa, S. -I. Nishimura, S. Wada, T. Karino, T. Nishikawa, K. Ijiro, M. Shimomura”
“Polymer Journal,34(3),166-174,2002”

Electric Conductivity of Nucleic Acid Polymer Monolayer
“Yuichi Hashimoto, Kuniharu Ijiro, Tetsuro Sawadaishi and Masatsugu Shimomura”
“International Journal of Nanoscience,1(5&6),707-711,2002”

Controlled Aggregation of Azobenzene Based on DNA-Mimetics at the Air-Water Interface
“Kuniharu Ijiro, Jin Matsumoto, Mitsuhiko Morisue and Masatsugu Shimomura”
“International Journal of Nanoscience,1(5&6),597-601,2002”

Circular Arrangement of Azobenzene Chromophores in the Nucleoamphiphile Monolayer by Base-Pairing with Cyclic DNA
“Jin Nishida, Jin Matsumoto, Mitsuhiko Morisue, Kuniharu Ijiro, Masatsugu Shimomura”
“International Journal of Nanoscience,1(5&6),677-681,2002”

Molecular Recognition of Nucleobeses Attached to Self-Assembled Monolayers Detected by Chemical Rrce Microscopy and Quartz Crystal Microbalance
“Hiroshi Sunami, Kuniharu Ijiro and Masatsugu Shimomura”
“International Journal of Nanoscience,1(5&6),667-671,2002”

Stretching of Single DNA Molecules by Langmuir-Blodgett Method
“Yasutaka Matsuo, Kuniharu Ijiro, Masatsugu Shimomura”
“International Journal of Nanoscience,1(5&6),695-699,2002”

導電性原子間力顕微鏡を用いたポリチオフェン細線の微小領域光導電性測定
橋本裕一・澤田石哲郎・居城邦治・下村政嗣
“高分子論文集,59(10),651-655,2002”

2001年

Two-Dimensional Patterning of Nanoparticles Using Dissipative Structures
“T. Sawadaishi, K. Ijiro, M. Shimomura, Y. Shiraishi, N. Toshima, T. Yonezawa, T. Kunitake”
“Mol. Cryst. Liq. Cryst.,371,123-126,2001”

Photopolymerization of the Diacetylene Nucleobase Monolayers Controlled by Triplex Formation
“J. Matsumoto, K. Ijiro, M. Shimomura”
“Mol. Cryst. Liq. Cryst.,371,33-36,2001”

Two-Dimensional Nucleobase Self-Organization Supported by Base-Pairing and Stacking at the Air-Water Interface.
“M.Morisue, K.Ijiro, M.Shimomura”
“Mol. Cryst. Liq. Cryst.,371,379-382,2001”

Fabrication and Photoconductivity Measurement of Mesoscopic 2-D Patterned DNA.
“K.Ijiro, T.Sawadaishi, M.Shimomura”
“Mol. Cryst. Liq. Cryst.,371,375-378,2001”

Nucleobase Mapping of Self-Assembled Monolayers by Chemical Force Microscopy
“H. Sunami, K. Ijiro, O. Karthaus, S. Kraemer, S. Mittler, W. Knoll, M. Shimomura.”
“Mol. Cryst. Liq. Cryst.,371,151-154,2001”

Direct Observation of Bimodal Amphiphilic Surface Structures of Zeolite Particles for a Novel Liquid-Liquid Phase Boundary Catalysis
“S. Ikeda, H. Nur, T. Sawadaishi, K. Ijiro, M. Shimomura, B. Ohtani”
“Langmuir,17(26),7976-7979,2001”

2000年以前

Molecular Recognition and Photopolymerization of Nucleobase Monolayer Containing Diacetylene Group at the Air-Water Interface
“J.Matsumoto, K.Ijiro, M.Shimomura”
“Chem.Lett.,,1280-1281,2000”

Effect of Polynucleotides on Fluorescence Quenching in Monolayers at the Air-Water Interface
“K.Ijiro, T.Ikeda, M.Shimomura”
“Mol. Cryst. Liq. Cryst.,327,45-48,1999”

Molecular Recognition and Monolayer Formation of Azobenzene-containig Nucleobase Amphiphile Assisited by Cis→Trans Photoisomerization at the Air-Water Interface
“M.Morisue, H.Nakamura, K.Ijiro, M.Shimomura”
“Mol. Cryst. Liq. Cryst,337,457-460,1999”

Direct in Situ Observation of a Lipid Monolayer-DNA Complex at the Air-Water Interface by X-ray Reflectometry
“K.Kago, H.Matsuoka, R.Yoshitomi, H.Yamaoka, K.Ijiro, M.Shimomura”
“Langmuir,15(16),5193-5196,1999”

Preparation of DNA-Based Molecular Assemblies by Self-Organization. From Nanometer Scale to Mesoscopic Scale
“M.Shimomura, J.Matsumoto, F.Nakamura, T.Ikeda, T.Fukazawa, K.Hasebe, T.Sawadaishi, K.Ijiro”
“Polymer J.,31,1115-1120 ,1999”

Mesoscopic Pattern Formation of Nanostructured Polymer Assemblies
“N. Maruyama, T. Koito, T. Sawadaishi, O. Karthaus, K. Ijiro, N. Nishi, S. Tokura, S.Nishimura, M. Shimomura”
“Supramol. Sci.,5,331-336,1998”

Construction of two-dimensional DNA-mimetics: Supramolecular Architecture with Highly Stacked Base-Pairs of Amphiphilic Adenine and Thymine at the Air-Water Interface
“F.Nakamura, K.Ijiro, M.Shimomura”
“Thin Solid Films,327-329,603-606,1998”

Aggregation of Dendrimers with a Photochromic Dithienylethene Core Group on the Mica Surface-Atomic Force Microscopic Imaging
“J. Hellmann, M. Hamana, O. Karthaus, K. Ijiro, M.Shimomura, M. Irie”
“Jpn.J.Appl.Phys.,37,L816-L819,1998”

Relationship between Surface Morphology and Electroabsorption spectrum of an Oxacyanine Chromophore in a Mixed Langmuir-Blodgett Film
“N. Ohta, M.Nakamura, I. Yamazaki, M.Shimomura, K.Ijiro”
“Langmuir,14(21),6226-6230,1998”

Organization of Two-Dimensional DNA-Mimetics at the Air-Water Interface
“K. Ijiro, F. Nakamura, M. Shimomura”
“Molecular Recognition and Inclusion,,361-364,1998”

Synthesis and Self-Organisation of New Cyclodextrin Amphiphile
“T. Sukegawa, M. Matsuda, S.-I. Nishimura, M. Shimomura, K. Ijiro, O. Karthaus”
“Molecular Recognition and Inclusion,,519-522,1998”

PROTEIN-DNA DOUBLE AND TRIPLE LAYERS – INTERACTION OF BIOTINYLATED DNA FRAGMENTS WITH SOLID SUPPORTED STREPTAVIDIN LAYERS
“K. Ijiro, H. Ringsdorf, E. Birchhirschfeld, S. Hoffmann, U. Schilken, M. Strube”
“Langmuir,14(10),2796-2800,1998”

Two-Dimensional DNA-Mimetic Molecular Organizations at the Air-Water Interface
“M.Shimomura, F.Nakamura, K.Ijiro, H.Taketsuna, M.Tanaka, H.Nakamura, K.Hasebe”
“J.Am.Chem.Soc.,119(9),2341-2342,1997”

Mesoscopic Patterns of DNA-Amphiphile Complexes
“M. Shimomura, O. Karthaus, N. Maruyama, K. Ijiro, T. Sawadaishi, S. Tokura, N. Nishi”
“Reports on Progress in Polymer Physics in Japan,40,523-524,1997”

DNA Monolayers Complexed with Amphiphilic Intercalator at the Air-Water Interface
“K.Ijiro, M.Shimomura, M.Tanaka, H.Nakamura, K.Hasebe”
“Thin Solid Films,284,285,780-783,1996”

Chiral Crystal Formation of Octadecylcytosine Monolayer by Complementary Basepairing
“M.Shimomura,F.Nakamura, K.Ijiro, H.Taketsuna, M.Tanaka, H.Nakamura, K.Hasebe”
“Thin Solid Films,284,285,691-693,1996”